Meeting Reports & Public Documents
Joint Meeting of Subcommittee 1 and 3<
"Radiation Effects on Living Body: From Micro to Macro"
21-23 Jun. 2022
Lecture materials, explanatory materials, etc.
(Japanese only)
Workshop Announcement
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Greeting "Publication of the Record of the JSPS Research Group Meeting"
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Report Introduction
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DNA damage and mutation by ROS - Implication from Mth1, Ogg1, Mutyh triple-deficient mice
Dr. Kunihiko Sakumi, Kyushu University PDF Dr. Sakumi, Reference
Germline mutation: de novo mutation in reproductive lineage cells. Genes Genet Syst. 2019 Apr 9;94(1):3-12. doi: 10.1266/ggs.18-00055. Mitochondria are responsible for cell death and survival - Cell death is mediated by mitochondria-derived ROS.
Dr. Sugako Oka, Kyushu University PDF Dr. Oka, Reference #1
Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. EMBO J. 2008 Jan 23;27(2):421-32. doi: 10.1038/sj.emboj.7601975. Dr. Oka, Reference #2
Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease. Sci Rep. 2016 Nov 29;6:37889. doi: 10.1038/srep37889. Dr. Oka, Reference #3
ROS control in human iPS cells reveals early events in spontaneous carcinogenesis. Carcinogenesis. 2020 Mar 13;41(1):36-43. doi: 10.1093/carcin/bgz081. Dr. Oka, Reference #4
Endogenous ROS production in early differentiation state suppresses endoderm differentiation via transient FOXC1 expression. Cell Death Discov. 2022 Apr 1;8(1):150. doi: 10.1038/s41420-022-00961-2. Comments from Dr. Masako Bando PDF
Dr. Kunihiko Sakumi, Kyushu University PDF Dr. Sakumi, Reference
Germline mutation: de novo mutation in reproductive lineage cells. Genes Genet Syst. 2019 Apr 9;94(1):3-12. doi: 10.1266/ggs.18-00055. Mitochondria are responsible for cell death and survival - Cell death is mediated by mitochondria-derived ROS.
Dr. Sugako Oka, Kyushu University PDF Dr. Oka, Reference #1
Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. EMBO J. 2008 Jan 23;27(2):421-32. doi: 10.1038/sj.emboj.7601975. Dr. Oka, Reference #2
Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease. Sci Rep. 2016 Nov 29;6:37889. doi: 10.1038/srep37889. Dr. Oka, Reference #3
ROS control in human iPS cells reveals early events in spontaneous carcinogenesis. Carcinogenesis. 2020 Mar 13;41(1):36-43. doi: 10.1093/carcin/bgz081. Dr. Oka, Reference #4
Endogenous ROS production in early differentiation state suppresses endoderm differentiation via transient FOXC1 expression. Cell Death Discov. 2022 Apr 1;8(1):150. doi: 10.1038/s41420-022-00961-2. Comments from Dr. Masako Bando PDF
